Precision Medicine Initiative, this is the name of the new research announced by President Obama and launched with $215 million investment, effort to revolutionize how we improve health and treat disease. The Precision Medicine Initiative will pioneer a new model of patient-powered research that promises to accelerate biomedical discoveries and provide clinicians with new tools, knowledge, and therapies to select which treatments will work best for which patients. Most medical treatments have been designed for the “average patient”. As a result, treatments can be very successful for some patients but not for others. This is changing with this innovative approach that takes into account differences in people’s genes. Precision medicine gives clinicians tools to better understand the complex mechanisms underlying a patient’s health, disease, or condition, and to better predicts which treatments will be most effective. Advances in precision medicine have already led to powerful new discoveries and several new treatments that are tailored to specific characteristics of individuals, such as a person’s genetic makeup, or the genetic profile of an individual’s tumor. Precision Medicine will leverage advances in genomics, emerging methods for managing and analyzing large data sets while protecting privacy, and health information technology to accelerate biomedical discoveries.